Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020870 | 1.00 | POLB (0.46) | POLBABCG2PPARGPPARDPPARA | |
| SCHEMBL11043542 | 0.80 | PPARG (0.72) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL11043538 | 0.80 | PPARG (0.72) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL7648311 | 0.79 | PPARG (0.41) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL5032476 | 0.78 | GRM2 (0.72) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL5032472 | 0.78 | GRM2 (0.72) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL154581 | 0.77 | ABCG2 (0.65) | POLBABCG2PPARAMEN1KMT2A | |
| SCHEMBL1206856 | 0.77 | ABCG2 (0.65) | POLBABCG2PPARAMEN1KMT2A | |
| SCHEMBL11025084 | 0.77 | PPARG (0.51) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL11024302 | 0.77 | PPARG (0.51) | PPARGPPARDPPARALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056172-B1 | PHENOXY- AND THIOPHENOXY COMPOUNDS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | FISONS plc (GB) | 1985-04-03 | — | — | EP | disclosed |