Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.61 |
| ▸ | HTR1B | P28222 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019528 | 0.86 | KDM4E (0.56) | HTR7HTR1BKDM4EALDH1A1HRH1 | |
| SCHEMBL11020751 | 0.84 | HTR7 (0.46) | HTR7KDM4EALDH1A1 | |
| SCHEMBL11019562 | 0.82 | TDP1 (0.47) | HTR7HTR1BKDM4EALDH1A1 | |
| SCHEMBL11020735 | 0.80 | KDM4E (0.67) | HTR7HTR1BKDM4EALDH1A1HRH1 | |
| SCHEMBL11022797 | 0.80 | HTR1B (0.55) | HTR7HTR1BKDM4EHRH1 | |
| SCHEMBL11019492 | 0.80 | HTR7 (0.56) | HTR7HTR1BKDM4EALDH1A1HRH1 | |
| SCHEMBL11019533 | 0.79 | KDM4E (0.58) | HTR7HTR1BKDM4EALDH1A1HRH1 | |
| SCHEMBL11024366 | 0.79 | KDM4E (0.58) | HTR7HTR1BKDM4EALDH1A1HRH1 | |
| SCHEMBL11021248 | 0.78 | KDM4E (0.53) | HTR7HTR1BKDM4EALDH1A1HRH1 | |
| SCHEMBL30492994 | 0.76 | HTR7 (0.64) | HTR7HTR1BALDH1A1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |