Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022671 | 0.89 | SMN1; SMN2 (0.50) | L3MBTL1TDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11019562 | 0.86 | TDP1 (0.47) | HTR7L3MBTL1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11019466 | 0.84 | SYK (0.48) | HTR7L3MBTL1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11022396 | 0.84 | HTR7 (0.61) | HTR7ALDH1A1KDM4E | |
| SCHEMBL9547466 | 0.81 | L3MBTL1 (0.65) | L3MBTL1TDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL5659890 | 0.79 | L3MBTL1 (0.67) | L3MBTL1TDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11019468 | 0.79 | MAOB (0.54) | HTR7L3MBTL1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11018432 | 0.78 | TSHR (0.42) | HTR7L3MBTL1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11018477 | 0.77 | L3MBTL1 (0.47) | L3MBTL1TDP1KCNA3MAPTLMNA | |
| SCHEMBL11022053 | 0.76 | RAB9A (0.41) | HTR7L3MBTL1ALDH1A1SMN1; SMN2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |