Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017187 | 0.85 | HSD17B10 (0.34) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11020098 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11018703 | 0.82 | KEAP1 (0.34) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11018005 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11021531 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11022685 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11017212 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11016793 | 0.76 | KEAP1 (0.39) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11021464 | 0.72 | KEAP1 (0.42) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL10967338 | 0.72 | KEAP1 (0.59) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |