Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.57 |
| ▸ | EBP | Q15125 | 3/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021857 | 0.83 | SIGMAR1 (0.55) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL11023197 | 0.81 | SIGMAR1 (0.59) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| SCHEMBL11022687 | 0.80 | SIGMAR1 (0.58) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| SCHEMBL11022701 | 0.79 | SIGMAR1 (0.53) | SIGMAR1FDPS | |
| SCHEMBL11022231 | 0.78 | SIGMAR1 (0.65) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| SCHEMBL9359567 | 0.75 | SIGMAR1 (0.64) | SIGMAR1EBPTAAR1FDPSSLC6A2 | |
| SCHEMBL10602857 | 0.74 | SIGMAR1 (0.54) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| SCHEMBL11024266 | 0.74 | SIGMAR1 (0.60) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| SCHEMBL11024416 | 0.74 | SIGMAR1 (0.57) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Demelverine SCHEMBL1516521 | 0.74 | SIGMAR1 (0.76) | SIGMAR1TAAR1FDPSSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082266-B1 | SUBSTITUTED 1,5-DIAMINOPENTANES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1985-01-09 | — | — | EP | disclosed |