Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021855 | 0.82 | SIGMAR1 (0.54) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL11022683 | 0.80 | SIGMAR1 (0.49) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL11022704 | 0.79 | SIGMAR1 (0.57) | SIGMAR1FDPS | |
| SCHEMBL11022228 | 0.78 | SIGMAR1 (0.50) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL10974964 | 0.74 | SIGMAR1 (0.70) | SIGMAR1KCNH2 | |
| SCHEMBL11022708 | 0.73 | TAAR1 (0.36) | SIGMAR1DRD2DRD4DRD3OPRM1 | |
| SCHEMBL11024413 | 0.73 | SIGMAR1 (0.46) | SIGMAR1KCNH2DRD3OPRM1FDPS | |
| SCHEMBL4254894 | 0.73 | SIGMAR1 (1.00) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL11024264 | 0.71 | SIGMAR1 (0.51) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL2538905 | 0.71 | SIGMAR1 (0.95) | SIGMAR1KCNH2DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082266-B1 | SUBSTITUTED 1,5-DIAMINOPENTANES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1985-01-09 | — | — | EP | disclosed |