Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CTSC | P53634 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155440 | 1.00 | TP53 (0.59) | TP53POLBTACR1HPRT1GAA | |
| Hydrochloric Acid SCHEMBL3861697 | 0.99 | TP53 (0.58) | TP53POLBTACR1HPRT1GAA | |
| Hydrochloric Acid SCHEMBL3861695 | 0.97 | TP53 (0.57) | TP53POLBTACR1HPRT1GAA | |
| SCHEMBL3867531 | 0.89 | REN (0.52) | TP53 | |
| SCHEMBL3867533 | 0.89 | REN (0.52) | TP53 | |
| SCHEMBL9487298 | 0.88 | TP53 (0.61) | TP53POLBTACR1GAARAB9A | |
| SCHEMBL9487303 | 0.88 | TP53 (0.61) | TP53POLBTACR1GAARAB9A | |
| SCHEMBL4432681 | 0.88 | ATM (0.63) | POLBGAARAB9AALDH1A1MEN1 | |
| SCHEMBL4432687 | 0.88 | ATM (0.63) | POLBGAARAB9AALDH1A1MEN1 | |
| SCHEMBL10955169 | 0.87 | LNPEP (0.51) | TP53POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1265669-A | Compounds that inhibit leukocyte adhesion mediated by VLA-4 | ELAND PHARMACEUTICALS CO (US) | 2000-09-06 | — | — | CN | disclosed |
| EP-0083857-B1 | DERIVATIVES OF HIPPURYL-L-PHENYLALANINE AND THEIR USE IN DETERMINING THE ACTIVITY OF CARBOXYPEPTIDASE A | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1985-06-05 | — | — | EP | disclosed |
| US-4414323-A | Method for measuring trace enzyme | FUJI PHOTO FILM CO., LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| EP-0083857-A1 | Derivatives of hippuryl-L-phenylalanine and their use in determining the activity of carboxypeptidase A | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1983-07-20 | — | — | EP | disclosed |