Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3538383 | 0.83 | KDM4E (0.41) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL5791591 | 0.77 | KDM4E (0.57) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL5610319 | 0.76 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL7194177 | 0.75 | KDM4E (0.38) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL3963715 | 0.75 | P2RX7 (0.48) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL5394033 | 0.74 | — | — | |
| SCHEMBL2459394 | 0.74 | KDM4E (0.47) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL6454171 | 0.72 | GRM4 (0.41) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL2928334 | 0.72 | EGLN2 (0.43) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL6808280 | 0.72 | NPC1 (0.40) | KDM4EMAPTALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60152477-A | — | — | None | — | — | JP | disclosed |
| JP-S60152477-A | NOVEL THIAZOLE DERIVATIVE AND PREPARATION THEREOF | KYORIN PHARMACEUT CO LTD | 1985-08-10 | — | — | JP | disclosed |