Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | SHBG | P04278 | 2/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414100 | 0.85 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT | |
| SCHEMBL10383759 | 0.85 | CYP19A1 (0.57) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT | |
| SCHEMBL11023741 | 0.83 | CYP3A4 (0.62) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT | |
| SCHEMBL4753154 | 0.83 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT | |
| SCHEMBL10377200 | 0.82 | CYP19A1 (0.78) | CYP19A1 | |
| SCHEMBL571657 | 0.81 | CYP3A4 (0.61) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT | |
| SCHEMBL23748331 | 0.80 | CYP3A4 (0.71) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT | |
| SCHEMBL674222 | 0.80 | CYP3A4 (0.71) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT | |
| SCHEMBL4747201 | 0.80 | CYP3A4 (0.71) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT | |
| SCHEMBL9640298 | 0.80 | SMN1; SMN2 (0.71) | ALDH1A1SMN1; SMN2CYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034115-B1 | PROCESS FOR THE PREPARATION OF 6-METHYLENE STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-06-08 | — | — | EP | disclosed |