Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023131 | 0.80 | APEX1 (0.47) | KDM4ETSHRKMT2AALDH1A1MAPT | |
| SCHEMBL11020558 | 0.79 | LMNA (0.46) | KDM4EGAATET2GLAPKM | |
| SCHEMBL11698511 | 0.77 | APEX1 (0.45) | KDM4EKMT2AMAPTCA1CA2 | |
| SCHEMBL11694667 | 0.76 | APEX1 (0.43) | KDM4ETSHRKMT2AALDH1A1MAPT | |
| SCHEMBL9180929 | 0.75 | LMNA (0.35) | LMNA | |
| SCHEMBL11695216 | 0.75 | LMNA (0.32) | KDM4EMAPTLMNAAPEX1 | |
| SCHEMBL11170960 | 0.74 | HPGD (0.43) | KDM4EGAAGLARECQLHSD17B10 | |
| SCHEMBL11381319 | 0.73 | ALDH1A1 (0.42) | KDM4EHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12640416 | 0.73 | MAOB (0.41) | KDM4ETSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11169905 | 0.72 | ALDH1A1 (0.37) | KDM4EHSD17B10TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129932-A1 | N,N,N',N'-tetra (hydroxyethyl)-5-acetylamino-2,4,6-triiodoisophtaloyldiglycinamide, a process for the preparation of said compound and an X-ray contrast agent containing said compound | DAGRA N.V. (NL) | 1985-01-02 | — | — | EP | disclosed |