Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347525 | 0.84 | LMNA (0.51) | LMNAKDM4ESMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL11014500 | 0.84 | LMNA (0.46) | LMNAKDM4EGAAGLASMN1; SMN2 | |
| SCHEMBL9816334 | 0.81 | LMNA (0.53) | LMNAKDM4ESMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL11700573 | 0.80 | LMNA (0.58) | LMNASMN1; SMN2TSHRKMT2AHSD17B10 | |
| SCHEMBL11694200 | 0.79 | LMNA (0.47) | LMNAKDM4ESMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL11690984 | 0.79 | LMNA (0.47) | LMNAKDM4ESMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL11023903 | 0.79 | KDM4E (0.42) | LMNAKDM4EGAAGLAPKM | |
| SCHEMBL9563844 | 0.78 | LMNA (0.58) | LMNAKDM4ESMN1; SMN2RECQL | |
| SCHEMBL11695398 | 0.78 | LMNA (0.56) | LMNASMN1; SMN2TSHRHSD17B10MAPK1 | |
| Ioglicic Acid SCHEMBL29699760 | 0.77 | LMNA (0.55) | LMNASMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129932-A1 | N,N,N',N'-tetra (hydroxyethyl)-5-acetylamino-2,4,6-triiodoisophtaloyldiglycinamide, a process for the preparation of said compound and an X-ray contrast agent containing said compound | DAGRA N.V. (NL) | 1985-01-02 | — | — | EP | disclosed |
| US-4307072-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1981-12-22 | — | — | US | disclosed |