Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994566 | 0.84 | ALDH1A1 (0.46) | TDP1MAPTLMNAPOLBMEN1 | |
| SCHEMBL314657 | 0.82 | SMN1; SMN2 (0.54) | TDP1MAPTLMNAPOLBMEN1 | |
| SCHEMBL314659 | 0.82 | SMN1; SMN2 (0.54) | TDP1MAPTLMNAPOLBMEN1 | |
| SCHEMBL314658 | 0.82 | SMN1; SMN2 (0.54) | TDP1MAPTLMNAPOLBMEN1 | |
| SCHEMBL11023973 | 0.81 | TDP1 (0.43) | TDP1MAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10454656 | 0.80 | MEN1 (0.62) | TDP1MAPTLMNAPOLBMEN1 | |
| SCHEMBL10454659 | 0.80 | MEN1 (0.62) | TDP1MAPTLMNAPOLBMEN1 | |
| SCHEMBL10998428 | 0.79 | LMNA (0.52) | TDP1MAPTLMNAPOLBMEN1 | |
| SCHEMBL10998399 | 0.79 | TDP1 (0.44) | TDP1MAPTLMNAPOLBMEN1 | |
| SCHEMBL10992241 | 0.79 | TDP1 (0.47) | TDP1MAPTLMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080746-B1 | NEW DIPHENYL ETHERS HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1985-08-21 | — | — | EP | disclosed |