SCHEMBL11024258

SCHEMBL11024258

O=C(CC(O)C(=O)OCCCCCCCCO)OCCCCCCCCO

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.42
ACHE P22303 6/20 0.39
NPSR1 Q6W5P4 2/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 1/20 0.33
RAD52 P43351 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28985417 1.00 NAAA (0.42) NAAAACHENPSR1MAPTMAPK1
SCHEMBL16413119 0.98 NAAA (0.39) NAAAACHENPSR1MAPTMAPK1
SCHEMBL3462460 0.92 NAAA (0.36) NAAAACHENPSR1MAPTMAPK1
SCHEMBL28085427 0.85 SMN1; SMN2 (0.41) NAAAACHENPSR1MAPTMAPK1
SCHEMBL11669561 0.85 SMN1; SMN2 (0.41) NAAAACHE
Alcohol SCHEMBL8816358 0.84 NAAA (0.61) NAAANPSR1MAPTMAPK1L3MBTL1
SCHEMBL5586417 0.84 TSHR (0.37) NAAAACHE
SCHEMBL9809378 0.83 ACHE (0.38) NAAAACHEGAA
SCHEMBL9099483 0.83 NAAA (0.66) NAAANPSR1MAPTMAPK1L3MBTL1
SCHEMBL1069145 0.83 NAAA (0.66) NAAANPSR1MAPTMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115282342-A Medical implant coating, preparation method thereof and medical implant 南方医科大学南方医院 2022-11-04 CN claimed
US-8968725-B2 Genipin cross-linked fibrin gels UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2015-03-03 US disclosed
US-20150004138-A1 METHOD OF REPAIRING A TISSUE DEFECT USING GENIPIN CROSS-LINKED FIBRIN GELS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-01-01 US disclosed
US-20130345321-A1 GENIPIN CROSS-LINKED FIBRIN GELS NIH-DEITR 2013-12-26 US disclosed
US-20120189584-A1 GENIPIN CROSS-LINKED FIBRIN GELS UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2012-07-26 US disclosed