Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1053266 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL33595 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL3911129 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL9099483 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL9242191 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL1055187 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL1069145 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL9099743 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL749593 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL8416064 | 0.96 | NAAA (0.66) | NAAANPSR1MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702693-A | DISSOLVING IN COMPOSITION CONSISTING OF A WATER-MISCIBLE SOLVENT, AN ORGANIC ACID AND AN EMOLLIENT; APPLYING TO SKIN AFTER REMOVAL OF CAST FOR BONE FRACTURE | DRAXIS HEALTH INC. (CA) | 1997-12-30 | — | — | US | disclosed |
| WO-1997020910-A1 | GYPSUM REMOVAL COMPOSITION AND METHOD OF REMOVING GYPSUM FROM SKIN | DRAXIS HEALTH INC. (CA) | 1997-06-12 | — | — | WO | disclosed |