SCHEMBL3626830

SCHEMBL3626830

CC(=O)N(C)c1cccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 11/20 0.67
GAA P10253 2/20 0.52
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
TSPO P30536 1/20 0.49
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
ELANE P08246 1/20 0.44
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20886923 0.90 SIGMAR1 (0.54) SIGMAR1GAANPC1RAB9ATSPO
SCHEMBL29666490 0.85 SIGMAR1 (0.67) SIGMAR1GAANR4A1NR4A2NR4A3
SCHEMBL1614544 0.85 SIGMAR1 (0.67) SIGMAR1GAANR4A1NR4A2NR4A3
SCHEMBL11872011 0.83 SIGMAR1 (0.65) SIGMAR1GAANR4A1NR4A2NR4A3
SCHEMBL8150820 0.83 SIGMAR1 (0.65) SIGMAR1GAANPC1RAB9AKDM4E
SCHEMBL10943508 0.83 SIGMAR1 (0.65) SIGMAR1GAANR4A1NR4A2NR4A3
SCHEMBL1839015 0.83 SIGMAR1 (0.65) SIGMAR1GAAKDM4E
SCHEMBL28259034 0.83 SIGMAR1 (0.65) SIGMAR1GAANR4A1NR4A2NR4A3
SCHEMBL11024265 0.82 GAA (0.77) SIGMAR1GAANPC1RAB9AKDM4E
SCHEMBL31425728 0.82 SIGMAR1 (0.59) SIGMAR1GAANPC1RAB9ANR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786483-B1 Process for an activated anionic lactam polymerisation INVENTA AG (CH) 2000-04-19 EP claimed
US-5756647-A LIQUID SYSTEM: CATALYST, ACTIVATOR AND SOLVENT EMS-INVENTA AG (CH) 1998-05-26 US claimed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US claimed
EP-0786483-A2 Process for an activated anionic lactam polymerisation EMS-INVENTA AG (CH) 1997-07-30 EP claimed
US-20230339910-A1 RAS INHIBITORS AND METHODS OF USING THE SAME JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) 2023-10-26 US disclosed
WO-2021152149-A1 RAS INHIBITORS AND METHODS OF USING THE SAME JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) 2021-08-05 WO disclosed
CN-105960402-A Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2016-09-21 CN disclosed
US-20140116112-A1 METHODS FOR DETERMINING THE PRESENCE OR ABSENCE OF CONTAMINANTS IN A SAMPLE K & D LABORATORIES, INC. (US) 2014-05-01 US disclosed
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
CN-101500410-A Granular controlled release agrochemical compositions and process for preparing same OMS INVEST INC (US) 2009-08-05 CN disclosed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed
WO-2006074261-A2 METHOD AND COMPOSITIONS FOR CONTROLLING RELEASE OF ORGANIC COMPOSITIONS MICHIGAN STATE UNIVERSITY (US) 2006-07-13 WO disclosed
EP-0786482-B1 Liquid system for the anionic lactam polymerisation INVENTA AG (CH) 2000-08-16 EP disclosed
US-5955094-A INTERCALATING A PHYLLOSILICATE WITH A PESTICIDE AMCOL INTERNATIONAL CORPORATION (US) 1999-09-21 US disclosed
US-5760164-A STORAGE STABILITY EMS-INVENTA AG (CH) 1998-06-02 US disclosed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US disclosed
EP-0808568-A1 Intercalates and exfoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1997-11-26 EP disclosed
CN-1161977-A Liquid-phase system. for polymerization of anionic lactam INVENTA AG (CH) 1997-10-15 CN disclosed
EP-0786482-A2 Liquid system for the anionic lactam polymerisation EMS-INVENTA AG (CH) 1997-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 SIGMAR1 429/4885GAA 3279/4885NPC1 3322/4885
US-20230339910-A1 RAS INHIBITORS AND METHODS OF USING THE SAME KRAS, NRAS, HRAS SIGMAR1 4731/4885GAA 1345/4885NPC1 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.