Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063480 | 0.86 | SHBG (0.53) | CA1CA2PTGS1PTGS2SHBG | |
| SCHEMBL4020654 | 0.81 | CYP2C9 (0.57) | CA1CA2ALDH1A1GAAKDM4E | |
| SCHEMBL3801816 | 0.78 | PTGS1 (0.68) | CA1CA2PTGS1PTGS2SHBG | |
| SCHEMBL68876 | 0.78 | SHBG (0.67) | CA1CA2PTGS1PTGS2SHBG | |
| SCHEMBL670778 | 0.76 | SHBG (0.58) | CA1CA2PTGS1PTGS2SHBG | |
| SCHEMBL1121332 | 0.76 | SHBG (0.64) | CA1CA2PTGS1PTGS2SHBG | |
| SCHEMBL1023068 | 0.76 | PTGS1 (0.55) | CA1CA2PTGS1PTGS2SHBG | |
| SCHEMBL19764508 | 0.74 | CA1 (0.50) | CA1CA2PTGS1PTGS2SHBG | |
| Dimethylamine SCHEMBL11406775 | 0.74 | SHBG (0.61) | CA1CA2PTGS1PTGS2SHBG | |
| SCHEMBL8306892 | 0.74 | CA1 (0.50) | CA1CA2PTGS1PTGS2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050261-B1 | MOULDING MASSES STABILIZED AGAINST THERMOLYSIS WITH A LOW MONOMER CONTENT | BAYER AG (DE) | 1985-08-14 | — | — | EP | disclosed |
| EP-0050261-A1 | Moulding masses stabilized against thermolysis with a low monomer content | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |
| US-4199494-A | Metal complexes of α-aminophosphonic acid half-esters and of α-a | CIBA-GEIGY CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |