SCHEMBL670778

SCHEMBL670778

Cc1cc(CO)cc(C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.58
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
ACHE P22303 2/20 0.50
PTGS1 P23219 3/20 0.48
PTGS2 P35354 3/20 0.48
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
HMGB1 P09429 1/20 0.43
CXCL12 P48061 1/20 0.43
KDM4E B2RXH2 2/20 0.43
CASP6 P55212 1/20 0.43
FYN P06241 1/20 0.42
ALOX5 P09917 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
CISD1 Q9NZ45 1/20 0.40
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8361500 0.87 SHBG (0.52) SHBGCA1CA2ACHEPTGS1
SCHEMBL283462 0.85 SHBG (0.80) SHBGCA1CA2ACHEPTGS1
SCHEMBL26262146 0.85 SHBG (0.50) SHBGCA1CA2ACHEPTGS1
SCHEMBL8760761 0.84 SHBG (0.70) SHBGCA1CA2ACHEPTGS1
SCHEMBL31265753 0.82 SHBG (0.62) SHBGCA1CA2ACHEPTGS1
SCHEMBL10821832 0.82 SHBG (0.62) SHBGCA1CA2ACHEPTGS1
SCHEMBL9709243 0.81 CA1 (0.50) SHBGCA1CA2ACHEPTGS1
SCHEMBL1785592 0.80 CYP2C9 (0.59) SHBGCA1CA2KDM4EALDH1A1
SCHEMBL31193211 0.80 CYP2C9 (0.59) SHBGCA1CA2KDM4EALDH1A1
SCHEMBL7910251 0.80 GSR (0.48) SHBGCA1CA2ACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118978430-A Synthesis method of triphenylring polyphenol compound 辽宁靖帆新材料有限公司 2024-11-19 CN claimed
CN-115369432-B Method for preparing nitrile by electrocatalytic coupling of primary alcohol and ammonia substance 大连理工大学 2024-08-20 CN claimed
CN-115369432-A Method for preparing nitrile by coupling electro-catalysis of primary alcohol and ammonia substances 大连理工大学 2022-11-22 CN claimed
EP-1341503-B1 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2008-02-13 EP claimed
US-20070149751-A1 Bulk manufacturing of supramolecular polymer forming polymer LINDSAY CHRISTOPHER I 2007-06-28 US claimed
US-6835212-B2 Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme WELLA AKTIENGESELLSCHAFT (DE) 2004-12-28 US claimed
EP-1341503-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2003-09-10 EP claimed
US-20030041391-A1 Agent and method for dyeing keratin fibres Wella GmbH (DE) 2003-03-06 US claimed
WO-2002047633-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2002-06-20 WO claimed
JP-2200679-A None JP disclosed
JP-5194564-A None JP disclosed
JP-61145172-A None JP disclosed
JP-61130329-A None JP disclosed
WO-2025095046-A1 RESIN COMPOSITION, DRY FILM, CURED PRODUCT, AND LIGHT EMITTING ELEMENT MOUNTED SUBSTRATE 太陽ホールディングス株式会社 2025-05-08 WO disclosed
EP-0003338-A2 Use of benzyl-phenols as antioxidants BAYER AG (DE) 1979-08-08 EP disclosed
US-4142035-A Polycondensates containing hydroxyquinoline end groups, their use for the preparation of polymers containing metals and metal containing polycondensates BAYER AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed
US-4137219-A STABILIZERS BAYER AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4119671-A OXIDATION OF HYDROXYBENZYL ALCOHOLS, PLATINUM CATALYST, ACTIVATORS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4020042-A Phenolic antioxidants THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-04-26 US disclosed
US-3983160-A Process for the preparation of hydroxyphenylacetonitriles BAYER AKTIENGESELLSCHAFT (DT) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030041391-A1 Agent and method for dyeing keratin fibres KRT18, AKR7A2, ADH5 SHBG 2881/4885CA1 1165/4885CA2 1930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.