Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL10634405 | 0.88 | ESR1 (0.54) | ESR1ESR2MMP2KCNJ1KCNH2 | |
| SCHEMBL7008328 | 0.84 | KMT2A (0.55) | KCNJ1KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL5306490 | 0.84 | MMP2 (0.53) | ESR1ESR2MMP2ALDH1A1MEN1 | |
| SCHEMBL1171038 | 0.83 | ESR1 (1.00) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL296781 | 0.83 | ESR1 (1.00) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL547164 | 0.83 | ESR1 (1.00) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL9810145 | 0.83 | ESR1 (1.00) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL27620476 | 0.81 | ESR1 (0.64) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4905759 | 0.81 | ESR1 (0.88) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4437809 | 0.81 | POLB (0.58) | ESR1ESR2KCNJ1KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153642-A2 | Process for the preparation of monomeric aromatic hydroxyurethanes | BAYER AG (DE) | 1985-09-04 | — | — | EP | disclosed |