Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205900 | 0.84 | POLB (0.67) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7008328 | 0.84 | KMT2A (0.55) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL11024329 | 0.81 | ESR1 (0.69) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL5264588 | 0.81 | POLB (0.50) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5261202 | 0.80 | KCNJ1 (0.45) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL151540 | 0.79 | ESR1 (0.52) | ALDH1A1KCNH2LOXL2ESR1ESR2 | |
| Iodide SCHEMBL5262196 | 0.79 | KCNJ1 (0.44) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL2350956 | 0.78 | ALDH1A1 (0.54) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL19734040 | 0.76 | ESR1 (0.55) | KMT2AMEN1NPC1RAB9AKCNH2 | |
| SCHEMBL20431221 | 0.76 | LOXL2 (0.52) | POLBALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |