Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95386 | 0.82 | CA1 (0.45) | HPGDKDM4EALDH1A1ERN1CA1 | |
| SCHEMBL6210588 | 0.77 | HTT (0.45) | HPGDMAPTTDP1KDM4ECYP1A2 | |
| SCHEMBL11024448 | 0.74 | ERN1 (0.46) | HPGDMAPTTDP1KDM4ECYP1A2 | |
| SCHEMBL10704960 | 0.73 | ERN1 (0.41) | HPGDMAPTTDP1KDM4ECYP1A2 | |
| SCHEMBL1541914 | 0.73 | ACHE (0.59) | HPGDMAPTKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL11315734 | 0.72 | ALDH1A1 (0.46) | HPGDALDH1A1CA1CA2CA9 | |
| SCHEMBL3192136 | 0.72 | CYP1A2 (0.43) | HPGDKDM4ECYP1A2ALDH1A1ERN1 | |
| SCHEMBL8940869 | 0.71 | ERN1 (0.44) | MAPTTDP1KDM4ECYP1A2ALDH1A1 | |
| SCHEMBL54507 | 0.70 | KMT2A (0.47) | HPGDMAPTTDP1KDM4ECYP1A2 | |
| SCHEMBL25934295 | 0.69 | KDM4E (0.47) | HPGDMAPTKDM4EALDH1A1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158159-A1 | Process for the synthesis of o-substituted oxime compounds and the conversion thereof into the corresponding hydroxylamine o-substituted | AlliedSignal Inc. (US) | 1985-10-16 | — | — | EP | disclosed |