Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027485 | 0.95 | ABCB11 (0.33) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11028715 | 0.95 | ABCB11 (0.33) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11027703 | 0.82 | CHRNB2 (0.33) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11025762 | 0.81 | ALDH1A1 (0.42) | TSHRLMNA | |
| SCHEMBL11027039 | 0.81 | CHRM2 (0.32) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11025767 | 0.79 | MEN1 (0.37) | TSHRLMNA | |
| SCHEMBL11027207 | 0.79 | CHRM2 (0.32) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11025027 | 0.78 | TSHR (0.45) | TSHRLMNA | |
| SCHEMBL11028482 | 0.77 | CHRM2 (0.33) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11027573 | 0.77 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479002-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES, PESTICIDES | UNION CARBIDE CORPORATION (US) | 1984-10-23 | — | — | US | claimed |
| US-4479002-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES, PESTICIDES | UNION CARBIDE CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| US-4341795-A | PESTICIDES; INSECTICIDES; MITICIDES | UNION CARBIDE CORPORATION (US) | 1982-07-27 | — | — | US | disclosed |