Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.47 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020122 | 0.83 | ADRB2 (0.69) | ADRB2ADRB1NPSR1TDP1 | |
| SCHEMBL11023789 | 0.82 | CYP4Z1 (0.45) | CYP4Z1CYP4F11CYP4F12ADRB2ADRB1 | |
| SCHEMBL11021128 | 0.79 | CYP4Z1 (0.49) | CYP4Z1CYP4F11CYP4F12ADRB2ADRB1 | |
| SCHEMBL11021132 | 0.79 | CYP4Z1 (0.49) | CYP4Z1CYP4F11CYP4F12ADRB2ADRB1 | |
| SCHEMBL12548347 | 0.78 | CYP4Z1 (0.58) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 | |
| SCHEMBL10463270 | 0.78 | CYP1A2 (0.65) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 | |
| SCHEMBL10463522 | 0.78 | CYP1A2 (0.59) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 | |
| SCHEMBL1239542 | 0.77 | ALOX5 (0.65) | KMT2ACYP4Z1CYP4F11CYP4F12CYP4F2 | |
| Hydrochloric Acid SCHEMBL11489404 | 0.77 | CYP1A2 (0.58) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL11479609 | 0.77 | CYP4Z1 (0.57) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041491-B1 | NEW PARA-SUBSTITUTED 3-PHENOXY-1-ALKYLAMINO-PROPANOL-2-S HAVING BETA RECEPTOR BLOCKING PROPERTIES | Aktiebolaget Hässle (SE) | 1985-01-30 | — | — | EP | disclosed |