Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024149 | 1.00 | THRB (0.33) | THRBTSHRALDH1A1CES2CTSL | |
| SCHEMBL11026235 | 1.00 | THRB (0.33) | THRBTSHRALDH1A1CES2CTSL | |
| SCHEMBL1646256 | 1.00 | THRB (0.33) | THRBTSHRALDH1A1CES2CTSL | |
| SCHEMBL11027329 | 1.00 | THRB (0.33) | THRBTSHRALDH1A1CES2CTSL | |
| SCHEMBL11024529 | 1.00 | THRB (0.33) | THRBTSHRALDH1A1CES2CTSL | |
| SCHEMBL11027193 | 1.00 | THRB (0.33) | THRBTSHRALDH1A1CES2CTSL | |
| SCHEMBL11028371 | 0.98 | — | — | |
| SCHEMBL11027561 | 0.91 | — | — | |
| SCHEMBL1645138 | 0.72 | FBP1 (0.31) | — | |
| SCHEMBL7232125 | 0.72 | THRB (0.33) | THRBTSHRALDH1A1CES2GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038459-B1 | PROCESS FOR THE PREVENTION OF REVERSION DURING THE MANUFACTURE OF RUBBER VULCANISATES | BAYER AG (DE) | 1985-07-10 | — | — | EP | disclosed |
| US-4340695-A | Vulcanization system, rubber mixture containing said system and a process of vulcanization | BAYER AKTIENGESELLSCHAFT (DE) | 1982-07-20 | — | — | US | disclosed |
| EP-0038459-A1 | Process for the prevention of reversion during the manufacture of rubber vulcanisates | BAYER AG (DE) | 1981-10-28 | — | — | EP | disclosed |