Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027329 | 0.72 | THRB (0.33) | THRBCES2GMNNTP53POLB | |
| SCHEMBL11024149 | 0.72 | THRB (0.33) | THRBCES2GMNNTP53POLB | |
| SCHEMBL11026235 | 0.72 | THRB (0.33) | THRBCES2GMNNTP53POLB | |
| SCHEMBL11024529 | 0.72 | THRB (0.33) | THRBCES2GMNNTP53POLB | |
| SCHEMBL11024901 | 0.72 | THRB (0.33) | THRBCES2GMNNTP53POLB | |
| SCHEMBL11027193 | 0.72 | THRB (0.33) | THRBCES2GMNNTP53POLB | |
| SCHEMBL1646256 | 0.72 | THRB (0.33) | THRBCES2GMNNTP53POLB | |
| SCHEMBL20638553 | 0.70 | PTGS2 (0.41) | TP53ALDH1A1PTGS2 | |
| SCHEMBL11566892 | 0.70 | PTGS2 (0.46) | THRBMAPTALDH1A1GPR84PTGS2 | |
| SCHEMBL11562856 | 0.70 | PTGS2 (0.46) | THRBMAPTALDH1A1GPR84PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548462-B1 | Coating the surface with bisphenyl thiocompounds | NEMATEL DR. RUDOLPH EIDENSCHINK (DE) | 2003-04-15 | — | — | US | disclosed |
| EP-1127048-A1 | BISPHENYL THIOCOMPOUNDS | NEMATEL Dr. Rudolf Eidenschink (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026184-A1 | BISPHENYL THIOCOMPOUNDS | NEMATEL DR. RUDOLF EIDENSCHINK (DE) | 2000-05-11 | — | — | WO | disclosed |