Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028657 | 0.93 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP1A2THRBKMT2A | |
| SCHEMBL11024806 | 0.87 | KMT2A (0.38) | ALDH1A1TDP1CYP1A2KMT2AHTT | |
| SCHEMBL11023135 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP1A2THRBKMT2A | |
| SCHEMBL11026162 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP1A2THRBKMT2A | |
| SCHEMBL11027009 | 0.84 | KMT2A (0.42) | ALDH1A1TDP1CYP1A2THRBKMT2A | |
| SCHEMBL11024955 | 0.82 | THRB (0.41) | ALDH1A1TDP1THRBKMT2AHTT | |
| SCHEMBL11028007 | 0.81 | THRB (0.42) | ALDH1A1TDP1CYP1A2THRBKMT2A | |
| SCHEMBL11026876 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TDP1CYP1A2THRBKMT2A | |
| SCHEMBL11025521 | 0.81 | MAOB (0.41) | ALDH1A1TDP1THRBKMT2AHTT | |
| SCHEMBL11029438 | 0.80 | THRB (0.39) | ALDH1A1TDP1CYP1A2THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | disclosed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |