Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023120 | 0.92 | TSHR (0.41) | THRBTSHRALDH1A1POLBTDP1 | |
| SCHEMBL11025869 | 0.86 | ALDH1A1 (0.37) | TSHRALDH1A1POLBHTTFBP1 | |
| SCHEMBL11026911 | 0.85 | ALDH1A1 (0.40) | THRBTSHRALDH1A1POLBTDP1 | |
| SCHEMBL11027638 | 0.83 | THRB (0.42) | THRBTSHRALDH1A1POLBTDP1 | |
| SCHEMBL11025473 | 0.82 | ALDH1A1 (0.40) | THRBTSHRALDH1A1POLBTDP1 | |
| SCHEMBL11028007 | 0.80 | THRB (0.42) | THRBTSHRALDH1A1POLBTDP1 | |
| SCHEMBL11027727 | 0.80 | THRB (0.40) | THRBTSHRALDH1A1POLBTDP1 | |
| SCHEMBL11028237 | 0.79 | TSHR (0.42) | THRBTSHRALDH1A1FBP1HPGD | |
| SCHEMBL11029438 | 0.78 | THRB (0.39) | THRBTSHRALDH1A1POLBTDP1 | |
| SCHEMBL11027009 | 0.78 | KMT2A (0.42) | THRBTSHRALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | disclosed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |