Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029436 | 0.88 | PDK1 (0.35) | TSHRGPR35ALDH1A1MAPTNPSR1 | |
| SCHEMBL9775501 | 0.88 | ALDH1A1 (0.51) | TSHRALDH1A1CYP1A2TDP1MAPT | |
| SCHEMBL11029377 | 0.84 | ALDH1A1 (0.43) | TSHRGPR35ALDH1A1CYP1A2TDP1 | |
| SCHEMBL11029069 | 0.83 | ALDH1A1 (0.40) | TSHRGPR35ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11025857 | 0.82 | TSHR (0.42) | TSHRGPR35ALDH1A1CYP1A2TDP1 | |
| SCHEMBL11027707 | 0.81 | TSHR (0.34) | TSHRGPR35ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11025471 | 0.81 | TDP1 (0.43) | GPR35ALDH1A1CYP1A2TDP1MAPT | |
| SCHEMBL11028004 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPTNPSR1POLB | |
| SCHEMBL11024952 | 0.77 | MEN1 (0.34) | ALDH1A1CYP1A2TDP1MAPTMEN1 | |
| SCHEMBL11026161 | 0.76 | ALDH1A1 (0.45) | TSHRGPR35ALDH1A1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | disclosed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |