Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025518 | 0.88 | TSHR (0.42) | ALDH1A1TSHRGPR35NPC1RECQL | |
| SCHEMBL11027707 | 0.85 | TSHR (0.34) | PDK1ALDH1A1TSHRGPR35NPC1 | |
| SCHEMBL11021342 | 0.83 | ALDH1A1 (0.44) | PDK1ALDH1A1TSHRGPR35KMT2A | |
| SCHEMBL11025303 | 0.81 | PDK1 (0.35) | PDK1ALDH1A1TSHRGPR35NPC1 | |
| SCHEMBL9775501 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TSHRNPC1KMT2AMAPT | |
| SCHEMBL11026161 | 0.80 | ALDH1A1 (0.45) | PDK1ALDH1A1TSHRGPR35KMT2A | |
| SCHEMBL11023130 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRGPR35KMT2AMAPT | |
| SCHEMBL11025471 | 0.79 | TDP1 (0.43) | ALDH1A1GPR35RECQLKMT2AMAPT | |
| SCHEMBL11028004 | 0.79 | ALDH1A1 (0.38) | PDK1ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11024952 | 0.78 | MEN1 (0.34) | PDK1ALDH1A1RECQLKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | disclosed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |