SCHEMBL11025532

SCHEMBL11025532

NC(=S)Nn1cnc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA3 P07451 2/20 0.45
CA4 P22748 2/20 0.45
CA6 P23280 2/20 0.45
CA5A P35218 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
CA13 Q8N1Q1 2/20 0.45
CA14 Q9ULX7 2/20 0.45
CA5B Q9Y2D0 2/20 0.45
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4384670 0.84 HSD17B10 (0.56) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL4447451 0.83 ALOX15 (0.51) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL707209 0.83 ALOX15 (0.58) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL204727 0.77 ALOX15 (0.64) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL6954737 0.76 ALOX15 (0.58) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL1800353 0.76 TDP1 (0.48) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
Pyridine SCHEMBL22610188 0.75 ALOX15 (0.48) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL15022038 0.75 TDP1 (0.52) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL1685055 0.75 HSD17B10 (0.61) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL28721775 0.73 ALOX15 (0.43) ALOX15HSD17B10CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0049656-B1 PURIFICATION DEVICE FOR REMOVING HEAVY METALS FROM CONTAMINATED AQUEOUS EFFLUENTS Commissariat à l'Energie Atomique (FR) 1985-05-29 EP claimed
EP-0049656-A1 Purification device for removing heavy metals from contaminated aqueous effluents Commissariat à l'Energie Atomique (FR) 1982-04-14 EP disclosed
EP-0001949-A1 Lubricant compositions that contain phosphorus and nitrogen OROGIL (FR) 1979-05-16 EP disclosed