Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025532 | 0.84 | ALOX15 (0.51) | HSD17B10ALOX15CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL204727 | 0.82 | ALOX15 (0.64) | HSD17B10ALOX15CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6954737 | 0.77 | ALOX15 (0.58) | HSD17B10ALOX15CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4447451 | 0.77 | ALOX15 (0.51) | HSD17B10ALOX15CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL707209 | 0.77 | ALOX15 (0.58) | HSD17B10ALOX15CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15022038 | 0.77 | TDP1 (0.52) | HSD17B10ALOX15CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1685055 | 0.76 | HSD17B10 (0.61) | HSD17B10ALOX15CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29833600 | 0.76 | SMN1; SMN2 (0.56) | HSD17B10HTTTDP1TNFCYP11B1 | |
| SCHEMBL29833599 | 0.76 | SMN1; SMN2 (0.56) | HSD17B10HTTTDP1TNFCYP11B1 | |
| SCHEMBL239691 | 0.74 | HTT (0.48) | HSD17B10ALOX15CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131369-A1 | Novel Benzimidazole(Thio)Carbamates with Antiparasitic Activity and the Synthesis Thereof | INTERVET INTERNATIONAL B.V. (NL) | 2009-05-21 | — | — | US | disclosed |
| EP-1913009-A1 | NOVEL BENZIMIDAZOLE (THIO) CARBAMATES WITH ANTIPARASITIC ACTIVITY AND THE SYNTHESIS THEREOF | Intervet International BV (NL) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007014846-A1 | NOVEL BENZIMIDAZOLE (THIO) CARBAMATES WITH ANTIPARASITIC ACTIVITY AND THE SYNTHESIS THEREOF | INTERVET INTERNATIONAL B.V. (NL) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131369-A1 | Novel Benzimidazole(Thio)Carbamates with Antiparasitic Activity and the Synthesis Thereof | CYP2C8, CYP3A7, CYP8B1 | HSD17B10 1565/4885ALOX15 1927/4885CYP1A2 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.