SCHEMBL11025536

SCHEMBL11025536

CSNc1nc(SC)nc(N(SC)SC)n1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
ALDH1A1 P00352 1/20 0.34
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9037910 0.59 LMNA (0.55) LMNAALDH1A1MAPK1
SCHEMBL10920178 0.59 LMNA (0.55) LMNAALDH1A1MAPK1
SCHEMBL7537282 0.58 HSP90AB1 (0.48) LMNAALDH1A1MAPK1
SCHEMBL11026801 0.57 ALDH1A1 (0.35) LMNAALDH1A1
SCHEMBL11166627 0.57 LMNA (0.46) LMNAALDH1A1MAPK1
SCHEMBL8061638 0.55 LMNA (0.54) LMNAALDH1A1
Simetryn SCHEMBL8409672 0.55 LMNA (0.54) LMNAALDH1A1
SCHEMBL8061227 0.55 LMNA (0.48) LMNAALDH1A1
Simetryn SCHEMBL67522 0.55 LMNA (0.54) LMNAALDH1A1
SCHEMBL14338996 0.53 HSP90AB1 (0.50) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0078784-B1 THIO-SUBSTITUTED-1,3,5-TRIAZINE-DIAMINES AND -TRIAMINES USEFUL AS PREVULCANIZATION INHIBITORS MONSANTO COMPANY (US) 1985-07-03 EP disclosed
US-4460769-A Thio-amino-1,3,5-triazines MONSANTO COMPANY (US) 1984-07-17 US disclosed
EP-0078784-A1 Thio-substituted-1,3,5-triazine-diamines and -triamines useful as prevulcanization inhibitors MONSANTO COMPANY (US) 1983-05-11 EP disclosed