Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | FABP4 | P15090 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655267 | 1.00 | POLB (0.71) | POLBKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL24316125 | 0.88 | MAPK1 (0.76) | POLBKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL5657986 | 0.84 | LMNA (0.72) | POLBKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL30481056 | 0.84 | LMNA (0.72) | POLBKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL5658185 | 0.83 | MAPK1 (0.87) | POLBKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL29186487 | 0.83 | KDM4E (1.00) | POLBKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL30825085 | 0.83 | KDM4E (1.00) | POLBKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL12019215 | 0.83 | MEN1 (0.54) | POLBKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL428355 | 0.82 | MAPK1 (1.00) | POLBKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL18409238 | 0.82 | FABP4 (0.77) | POLBKDM4EALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059108-B1 | DERIVATIVES OF DIHYDROXYBENZOIC ACID | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4409240-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS, BRONCHODILATOR, AND ANTIARTHRITIC AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0059108-A1 | Derivatives of dihydroxybenzoic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-09-01 | — | — | EP | disclosed |