Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552837 | 0.92 | MAOB (0.38) | MAOBTSHRGPR35ALDH1A1HTT | |
| SCHEMBL11026177 | 0.88 | MAOB (0.36) | MAOBTSHRGPR35ALDH1A1LMNA | |
| SCHEMBL719824 | 0.87 | MAOB (0.56) | MAOBTSHRALDH1A1LMNAHTT | |
| SCHEMBL11025521 | 0.87 | MAOB (0.41) | MAOBTSHRGPR35ALDH1A1HTT | |
| SCHEMBL5604448 | 0.86 | MAOB (0.50) | MAOBTSHRGPR35ALDH1A1LMNA | |
| SCHEMBL11029380 | 0.85 | MAOB (0.40) | MAOBTSHRGPR35ALDH1A1HTT | |
| SCHEMBL11025770 | 0.83 | MAOB (0.41) | MAOBTSHRGPR35ALDH1A1HTT | |
| SCHEMBL499373 | 0.83 | GPR35 (0.50) | MAOBTSHRGPR35ALDH1A1HTT | |
| SCHEMBL11024091 | 0.81 | KMT2A (0.38) | MAOBTSHRGPR35ALDH1A1HTT | |
| SCHEMBL5490051 | 0.80 | GPR35 (0.47) | MAOBTSHRGPR35ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | disclosed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |