Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11024747 | 0.99 | ALDH1A1 (0.40) | ALDH1A1CDC25BCASP6RCE1TSHR | |
| SCHEMBL11026186 | 0.95 | ALDH1A1 (0.45) | ALDH1A1CDC25BCASP6RCE1TSHR | |
| SCHEMBL4650355 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CDC25BCASP6RCE1TSHR | |
| SCHEMBL10940102 | 0.73 | ALDH1A1 (0.61) | ALDH1A1CDC25BCASP6RCE1TSHR | |
| SCHEMBL21540073 | 0.73 | ALDH1A1 (0.55) | ALDH1A1CDC25BCASP6RCE1HSD17B10 | |
| SCHEMBL10955418 | 0.72 | ALDH1A1 (0.63) | ALDH1A1CDC25BCASP6RCE1TSHR | |
| SCHEMBL6151946 | 0.71 | ELANE (0.46) | ALDH1A1TSHRHSD17B10KDM4EMAPT | |
| SCHEMBL10951389 | 0.71 | ALDH1A1 (0.65) | ALDH1A1CDC25BCASP6RCE1TSHR | |
| Hydrochloric Acid SCHEMBL10950384 | 0.70 | ALDH1A1 (0.63) | ALDH1A1CDC25BCASP6RCE1TSHR | |
| SCHEMBL28222134 | 0.69 | CYP3A4 (0.43) | ALDH1A1TSHRHSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060329-B1 | PROCESS FOR THE PREPARATION OF ORIENTATION LAYERS FOR LIQUID-CRYSTAL DISPLAYS, AND DISPLAYS CONTAINING THESE ORIENTATION LAYERS | SIEMENS AKTIENGESELLSCHAFT (DE) | 1985-06-05 | — | — | EP | disclosed |
| EP-0060329-A1 | Process for the preparation of orientation layers for liquid-crystal displays, and displays containing these orientation layers | SIEMENS AKTIENGESELLSCHAFT (DE) | 1982-09-22 | — | — | EP | disclosed |