SCHEMBL4650355

SCHEMBL4650355

Nc1ccc(Cc2ccc(N)c(OC(=O)O)c2)cc1OC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
CDC25B P30305 1/20 0.55
CASP6 P55212 1/20 0.55
RCE1 Q9Y256 1/20 0.55
GAA P10253 4/20 0.49
TSHR P16473 3/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPT P10636 2/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47
CFD P00746 1/20 0.44
CYP3A4 P08684 1/20 0.42
KLKB1 P03952 1/20 0.39
CTSB P07858 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11025883 0.83 ALDH1A1 (0.41) ALDH1A1CDC25BCASP6RCE1GAA
Hydrochloric Acid SCHEMBL11024747 0.82 ALDH1A1 (0.40) ALDH1A1CDC25BCASP6RCE1GAA
SCHEMBL10940102 0.81 ALDH1A1 (0.61) ALDH1A1CDC25BCASP6RCE1GAA
SCHEMBL379937 0.79 KLKB1 (0.53) ALDH1A1GAATSHRKDM4EMAPT
SCHEMBL1954453 0.79 ALDH1A1 (0.52) ALDH1A1GAATSHRKDM4EMAPT
SCHEMBL7754586 0.79 MAPT (0.48) ALDH1A1CDC25BCASP6RCE1GAA
SCHEMBL376800 0.79 ALDH1A1 (0.52) ALDH1A1GAATSHRKDM4EMAPT
SCHEMBL1551903 0.77 KDM4E (0.44) ALDH1A1KDM4EMAPTMEN1POLB
SCHEMBL13929946 0.76 TPMT (0.34) ALDH1A1CDC25BCASP6RCE1TSHR
SCHEMBL11026186 0.75 ALDH1A1 (0.45) ALDH1A1CDC25BCASP6RCE1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0362649-B1 Radiation-sensitive compositions and their use BASF AG (DE) 1994-03-02 EP claimed
EP-0362644-B1 RADIATION-SENSITIVE COMPOSITIONS AND THEIR USE BASF Aktiengesellschaft (DE) 1993-05-26 EP claimed
EP-0041677-B1 RADIATION REACTIVE PRECURSORS OF HIGHLY HEAT-RESISTANT POLYMERS, AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1984-12-27 EP claimed
EP-0041677-A2 Radiation reactive precursors of highly heat-resistant polymers, and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-12-16 EP claimed
EP-1000123-B1 USE OF REACTIVE DYES FOR DYEING HAIR BASF SE (DE) 2008-09-10 EP disclosed
EP-0929610-B1 REACTIVE DYES WITH A HETEROCYCLIC ANCHOR DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-08-28 EP disclosed
EP-1027387-B1 DOUBLE REACTIVE DYES DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-02-06 EP disclosed
EP-0970148-B1 OLIGOMERIC AZO DYES BASF AG (DE) 2001-06-13 EP disclosed
EP-0733680-B1 Reactive dyes with a benzo-anellated heterocycle as reactive group BASF AG (DE) 2000-01-05 EP disclosed
EP-0799260-B1 PROCESS FOR PREPARING DYED MELAMINE-FORMALDEHYDE CONDENSATION PRODUCTS BASF AG (DE) 1999-05-06 EP disclosed
EP-0799260-A1 PROCESS FOR PREPARING DYED MELAMINE-FORMALDEHYDE CONDENSATION PRODUCTS BASF AKTIENGESELLSCHAFT (DE) 1997-10-08 EP disclosed
EP-0497174-B1 Bifunctional reactive dyes containing vinylsulfone/pyrimidine groups BAYER AG (DE) 1997-03-05 EP disclosed
EP-0119441-A2 Reactive dyes with substituted 4-fluoropyridaz-6-one groups BASF Aktiengesellschaft (DE) 1984-09-26 EP disclosed
EP-0040806-B1 WATER-SOLUBLE, COLOURED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-19 EP disclosed
EP-0012969-B1 WATER-SOLUBLE FIBRE-REACTIVE COMPOUNDS AND THEIR USE IN FIBRE FINISHING,ESPECIALLY AS DYESTUFFS,AND DIHALOGENO-PYRIDAZONYL-CARBOXYLIC AND SULFONIC ACID HALIDES AND THEIR USE AS FIBRE-REACTIVE ANCHORS,AS WELL AS PROCESS FOR THE PREPARATION OF THESE COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1983-06-08 EP disclosed
EP-0045488-A2 Water-soluble fibre-reactive compounds and their use in finishing textiles, as well as the beta-chloroethyl-sulfonyl-methyl-benzoic-acid halogenides, and their use as a fibre-reactive anchor HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-10 EP disclosed
EP-0041678-A2 Process for the production of highly heat-resistant relief structures, and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed
EP-0041677-A2 Radiation reactive precursors of highly heat-resistant polymers, and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed
EP-0040806-A2 Water-soluble, coloured compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-02 EP disclosed
EP-0012969-A2 Water-soluble fibre-reactive compounds and their use in fibre finishing,especially as dyestuffs,and dihalogeno-pyridazonyl-carboxylic and sulfonic acid halides and their use as fibre-reactive anchors,as well as process for the preparation of these compound HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed