Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024643 | 0.90 | MEN1 (0.38) | MEN1KMT2AAIMP2CA2ALDH1A1 | |
| SCHEMBL9826628 | 0.89 | MEN1 (0.47) | MEN1KMT2AAIMP2CA2LMNA | |
| SCHEMBL11027071 | 0.88 | MEN1 (0.38) | MEN1KMT2AAIMP2CA2L3MBTL1 | |
| SCHEMBL11213080 | 0.88 | MEN1 (0.38) | MEN1KMT2AAIMP2CA2L3MBTL1 | |
| SCHEMBL11037968 | 0.87 | CA2 (0.48) | MEN1KMT2AAIMP2CA2L3MBTL1 | |
| SCHEMBL11039272 | 0.87 | CA2 (0.43) | MEN1KMT2AAIMP2CA2L3MBTL1 | |
| SCHEMBL11215438 | 0.85 | FFAR1 (0.43) | MEN1KMT2AAIMP2CA2L3MBTL1 | |
| SCHEMBL11202160 | 0.85 | MAPT (0.41) | MEN1KMT2AAIMP2LMNAALDH1A1 | |
| SCHEMBL9824715 | 0.83 | CA2 (0.60) | CA2 | |
| SCHEMBL11206081 | 0.83 | MEN1 (0.42) | MEN1KMT2AAIMP2CA2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068261-B1 | N-OXACYCLYL-ALKYLPIPERIDINE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |
| EP-0068261-A1 | N-oxacyclyl-alkylpiperidine derivatives, their preparation, pharmaceutical preparations containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |