Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025933 | 0.90 | MEN1 (0.48) | MEN1KMT2AAIMP2CA2ALDH1A1 | |
| SCHEMBL11039272 | 0.88 | CA2 (0.43) | MEN1KMT2AAIMP2CA2DRD2 | |
| SCHEMBL11037968 | 0.88 | CA2 (0.48) | MEN1KMT2AAIMP2CA2DRD2 | |
| SCHEMBL11202160 | 0.86 | MAPT (0.41) | MEN1KMT2AAIMP2DRD2DRD4 | |
| SCHEMBL11027071 | 0.84 | MEN1 (0.38) | MEN1KMT2AAIMP2CA2DRD2 | |
| SCHEMBL11213080 | 0.84 | MEN1 (0.38) | MEN1KMT2AAIMP2CA2DRD2 | |
| SCHEMBL6956315 | 0.82 | PRMT5 (0.47) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL11215438 | 0.82 | FFAR1 (0.43) | MEN1KMT2AAIMP2CA2FFAR1 | |
| SCHEMBL11206081 | 0.80 | MEN1 (0.42) | MEN1KMT2AAIMP2CA2ALDH1A1 | |
| SCHEMBL11102654 | 0.79 | LMNA (0.48) | MEN1KMT2ACA2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068261-B1 | N-OXACYCLYL-ALKYLPIPERIDINE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |
| EP-0068261-A1 | N-oxacyclyl-alkylpiperidine derivatives, their preparation, pharmaceutical preparations containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |