Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024643 | 0.86 | MEN1 (0.38) | ALDH1A1AIMP2MEN1KMT2ADRD2 | |
| SCHEMBL11037968 | 0.86 | CA2 (0.48) | AIMP2MEN1KMT2ADRD2DRD4 | |
| SCHEMBL11025933 | 0.85 | MEN1 (0.48) | MAPTALDH1A1SMN1; SMN2AIMP2MEN1 | |
| SCHEMBL11098301 | 0.83 | RAB9A (0.45) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1545676 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11039272 | 0.82 | CA2 (0.43) | AIMP2MEN1KMT2ADRD2DRD4 | |
| SCHEMBL11027071 | 0.78 | MEN1 (0.38) | MAPTALDH1A1SMN1; SMN2AIMP2MEN1 | |
| SCHEMBL11213080 | 0.78 | MEN1 (0.38) | MAPTALDH1A1SMN1; SMN2AIMP2MEN1 | |
| SCHEMBL5992714 | 0.77 | KDM4E (0.48) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6956315 | 0.77 | PRMT5 (0.47) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068261-A1 | N-oxacyclyl-alkylpiperidine derivatives, their preparation, pharmaceutical preparations containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |