Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | RARG | P13631 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348219 | 0.91 | PTGDR2 (0.42) | PTGDR2PTGDRGLATSHRALOX12 | |
| SCHEMBL7949638 | 0.88 | PTGDR (0.40) | PTGDR2PTGDRGLATSHRALOX12 | |
| SCHEMBL27262057 | 0.78 | SIGMAR1 (0.35) | PTGDR2PTGDRRARBRARGRARA | |
| SCHEMBL224914 | 0.75 | ALOX12 (0.50) | PTGDR2PTGDRGLATSHRALOX12 | |
| SCHEMBL27469641 | 0.72 | PTGDR (0.40) | PTGDR2PTGDRGLATSHRALOX12 | |
| SCHEMBL11809115 | 0.72 | PTGDR (0.41) | PTGDR2PTGDRGLATSHRALOX12 | |
| SCHEMBL9355910 | 0.71 | GLA (0.36) | PTGDR2PTGDRGLATSHRALOX12 | |
| SCHEMBL2498796 | 0.69 | GLA (0.48) | PTGDR2PTGDRGLATSHRALOX12 | |
| SCHEMBL8385833 | 0.69 | TP53 (0.43) | MEN1KMT2ATP53GAAACHE | |
| SCHEMBL14571978 | 0.69 | GLA (0.55) | PTGDR2PTGDRGLATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040286-B1 | POLYVINYL HALIDE RESIN COMPOSITIONS CONTAINING 1,3 DICARBONYL COMPOUNDS | PHOENIX CHEMICAL CORPORATION (US) | 1985-01-16 | — | — | EP | disclosed |