SCHEMBL27469641

SCHEMBL27469641

Cc1ccc(OP(=O)(O)OF)c(C2(C)CCCCC2)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGDR Q13258 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
RARB P10826 3/20 0.40
RARG P13631 3/20 0.40
RARA P10276 2/20 0.40
GLA P06280 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LPAR1 Q92633 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7949638 0.73 PTGDR (0.40) PTGDRPTGDR2RARBRARGRARA
SCHEMBL27455543 0.73 PTGDR2 (0.54) PTGDRPTGDR2NPC1RAB9A
SCHEMBL11026097 0.72 PTGDR2 (0.42) PTGDRPTGDR2RARBRARGRARA
SCHEMBL10348219 0.72 PTGDR2 (0.42) PTGDRPTGDR2RARBRARGRARA
SCHEMBL27453473 0.70 MEN1 (0.36) PTGDR2TSHRMEN1KMT2A
SCHEMBL224914 0.69 ALOX12 (0.50) PTGDRPTGDR2RARBRARGRARA
SCHEMBL9126703 0.67 F9 (0.42) PTGDRPTGDR2RARBRARGRARA
SCHEMBL21322453 0.65 PTGDR (0.55) PTGDRPTGDR2RARBRARGRARA
SCHEMBL27469640 0.65 NR3C1 (0.36) TSHR
SCHEMBL9269914 0.64 PTGDR (0.38) PTGDRPTGDR2RARBRARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1213078-C Olefine (co) polymer composition and its manufacturing method and catalyst for olefine (co) polymerization and its manufacturing method CHISSO CORP (JP) 2005-08-03 CN disclosed
CN-1146586-C Olefin homopolymer or copolymer composition and process for producing the same �����ɷ� 2004-04-21 CN disclosed
CN-1429850-A Olefine (co) polymer composition and its manufacturing method and catalyst for olefine (co) polymerization and its manufacturing method CHISSO CORP (JP) 2003-07-16 CN disclosed
CN-1191547-A Olefin (co) polymer composition and method for producing same, and catalyst for olefin (co) polymerization and method for producing same CHISSO CORP (JP) 1998-08-26 CN disclosed