Tetrahydrofuran

Tetrahydrofuran

SCHEMBL11026489

C1CCOC1.C1CCOC1.C1CCOCC1

nearest known ligand 0.89

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.89
TSHR P16473 2/20 0.50
TTR P02766 1/20 0.50
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL1724146 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
Cyclopropane SCHEMBL3744694 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL2846103 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL5386353 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL4788259 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL2848269 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL2845030 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL10713952 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL87670 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL4456224 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0053023-B1 HYDROXYLATION OF OLEFINS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-04-17 EP disclosed
US-4393253-A Hydroxylation of olefins EXXON RESEARCH & ENGINEERING CO. (US) 1983-07-12 US disclosed
EP-0053023-A1 Hydroxylation of olefins EXXON RESEARCH AND ENGINEERING COMPANY (US) 1982-06-02 EP disclosed
US-4314088-A Hydroxylation of olefins EXXON RESEARCH & ENGINEERING CO. (US) 1982-02-02 US disclosed