SCHEMBL4456224

SCHEMBL4456224

C1CCOCC1.C1CCOCC1.C1CCOCC1.C1CCOCC1

nearest known ligand 0.89

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.89
TSHR P16473 2/20 0.50
TTR P02766 1/20 0.50
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL1724146 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
Tetrahydrofuran SCHEMBL11026489 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
Cyclopropane SCHEMBL3744694 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL2846103 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL5386353 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL4788259 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL2848269 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL2845030 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL10713952 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A
SCHEMBL87670 1.00 ALDH1A1 (0.89) ALDH1A1TSHRTTRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105080604-B A kind of crosslinked polystyrene microsphere surface synthesis and the preparation method of immobilized N hydroxyphthalimides catalyst 中北大学 2017-09-05 CN claimed
CN-105080604-A Preparation method of crosslinked polystyrene microsphere surface synthesized and immobilized N-hydroxyphthalimide catalyst UNIV NORTH CHINA 2015-11-25 CN claimed
CN-102516564-B Soap-free preparation method of biodegradable polymer nanoparticles UNIV HUAZHONG SCIENCE TECH 2014-03-26 CN claimed
CN-102516564-A Soap-free preparation method of biodegradable polymer nanoparticles UNIV HUAZHONG SCIENCE TECH 2012-06-27 CN claimed
CN-101279956-B Matrix metalloprotease inhibitors and synthetic method thereof UNIV NANCHANG 2011-06-15 CN claimed
EP-4333899-A1 COMPOUNDS FOR TARGETING DEGRADATION OF BRUTON'S TYROSINE KINASE Biogen MA Inc. (US) 2024-03-13 EP disclosed
WO-2023204822-A1 PHENYL PHOSPHINE OXIDE COMPOUNDS AND METHODS OF USE THEREOF VIVACE THERAPEUTICS, INC. (US) 2023-10-26 WO disclosed
WO-2023109909-A1 AROMATIC HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND USES THEREOF 上海翊石医药科技有限公司 2023-06-22 WO disclosed
CN-115353512-A Heterocyclic urea compound and preparation method and application thereof 上海翊石医药科技有限公司 2022-11-18 CN disclosed
CN-109071530-B Fused pyrimidine piperidine ring derivatives, and preparation method and application thereof 上海艾力斯医药科技股份有限公司 2021-08-17 CN disclosed
EP-3759109-A1 SUBSTITUTED PYRROLIZINE COMPOUNDS AS HBV REPLICATION INHIBITORS GILEAD SCIENCES, INC. (US) 2021-01-06 EP disclosed
WO-2020135878-A1 IMIDAZOPYRIDINE DERIVATIVE AS FGFR AND VEGFR DUAL INHIBITOR 南京明德新药研发有限公司 2020-07-02 WO disclosed
CN-102593259-A Method for manufacturing solar cell AU OPTRONICS CORP 2012-07-18 CN disclosed
WO-2012084711-A1 N-SUBSTITUTED AZETIDINE DERIVATIVES MSD OSS B.V. (NL) 2012-06-28 WO disclosed
CN-102516564-A Soap-free preparation method of biodegradable polymer nanoparticles UNIV HUAZHONG SCIENCE TECH 2012-06-27 CN disclosed
WO-2009085819-A1 SURFACE ACTIVE SEGMENTED BLOCK COPOLYMERS BAUSCH & LOMB INCORPORATED (US) 2009-07-09 WO disclosed
CN-1257224-C Nano structural material model making method CHANGCHUN APPLIED CHEMISTRY (CN) 2006-05-24 CN disclosed
CN-1610547-A N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor LILLY CO ELI (US) 2005-04-27 CN disclosed
CN-1569956-A Nano structural material model making method CHANGCHUN APPLIED CHEMISTRY (CN) 2005-01-26 CN disclosed
US-5952448-A AN AROMATIC POLYIMIDE AMIC ESTER RANDOM COPOLYMER IS CHEMICALLY STABLE AND HAS EXCELLENT WORKABILITY IN EITHER LIQUID OR SOLID STATE, USED IN THE ELECTRONIC INDUSTRY AS A HEAT-RESISTANT INSULTING HIGH POLYMER MATERIAL KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1999-09-14 US disclosed