SCHEMBL11026537

SCHEMBL11026537

C=CC(C)OCCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
SIGMAR1 Q99720 3/20 0.37
IDO1 P14902 1/20 0.37
FAAH O00519 2/20 0.37
DHFR P00374 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
APP P05067 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15077436 0.81 TSHR (0.43) CA1CA2CA9SIGMAR1IDO1
SCHEMBL31059717 0.81 TSHR (0.43) CA1CA2CA9SIGMAR1IDO1
SCHEMBL11589791 0.80 TAAR1 (0.35) FAAH
SCHEMBL17581929 0.79 SIGMAR1 (0.44) CA1CA2CA9SIGMAR1IDO1
SCHEMBL4449191 0.78 CA1 (0.44) CA1CA2CA9SIGMAR1IDO1
SCHEMBL92354 0.78 CA1 (0.44) CA1CA2CA9SIGMAR1IDO1
SCHEMBL3959570 0.75 CA1 (0.41) CA1CA2CA9SIGMAR1IDO1
SCHEMBL10228461 0.75 CA1 (0.41) CA1CA2CA9SIGMAR1IDO1
SCHEMBL22762259 0.75 ALDH1A1 (0.44) CA1CA2CA9SIGMAR1IDO1
SCHEMBL94896 0.75 CA1 (0.46) CA1CA2CA9HCAR2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0049120-B1 PHENETHYLETHER DERIVATIVES, PROCESS FOR PREPARING SAME AND USES THEREOF IN COMBATTING TOBACCO BEETLES AND IN AUGMENTING OR ENHANCING THE AROMA OF PERFUMES, COLOGNES AND PERFUMED ARTICLES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-01-16 EP disclosed
US-4357319-A INSECTICIDES, ATTRACTANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-11-02 US disclosed
US-4328206-A Method of attracting and destroying tobacco beetles with alkyl phenethylethers INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-05-04 US disclosed
EP-0049120-A1 Phenethylether derivatives, process for preparing same and uses thereof in combatting tobacco beetles and in augmenting or enhancing the aroma of perfumes, colognes and perfumed articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-04-07 EP disclosed