SCHEMBL94896

SCHEMBL94896

CC([O])OCCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
TDP1 Q9NUW8 2/20 0.43
IDO1 P14902 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 2/20 0.41
HCAR2 Q8TDS4 1/20 0.41
SIGMAR1 Q99720 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22762259 0.83 ALDH1A1 (0.44) CA1CA2CA9IDO1ALDH1A1
SCHEMBL92354 0.83 CA1 (0.44) CA1CA2CA9IDO1ALDH1A1
SCHEMBL4449191 0.83 CA1 (0.44) CA1CA2CA9IDO1ALDH1A1
SCHEMBL6268780 0.82 CA1 (0.44) CA1CA2CA9TDP1IDO1
SCHEMBL17986293 0.80 TAAR1 (0.42) TSHR
SCHEMBL11022222 0.80 CA1 (0.43) CA1CA2CA9TDP1IDO1
SCHEMBL7107594 0.80 CA2 (0.56) CA1CA2CA9ALDH1A1
SCHEMBL3891204 0.79 CA1 (0.41) CA1CA2CA9IDO1ALDH1A1
SCHEMBL3959570 0.79 CA1 (0.41) CA1CA2CA9IDO1ALDH1A1
SCHEMBL10228461 0.79 CA1 (0.41) CA1CA2CA9IDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166218-A Antilipemic agents or antiglycemic agents HOFFMANN-LA ROCHE INC. (US) 1992-11-24 US claimed
EP-0140243-B1 PHENOXYPROPANOL AMINES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1988-11-09 EP claimed
US-4743604-A ANTIBESITY, ANTIDIABETIC, FEEDS HOFFMANN-LA ROCHE INC. (US) 1988-05-10 US claimed
CN-114488688-A Liquid crystal display element, method for producing same, and radiation-sensitive resin composition JSR株式会社 2022-05-13 CN disclosed
US-8362252-B2 Carbostyril compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-01-29 US disclosed
EP-1797082-B1 CARBOSTYRIL COMPOUND OTSUKA PHARMA CO LTD (JP) 2012-08-29 EP disclosed
EP-2426128-A1 Carbostyril compound Otsuka Pharmaceutical Co., Limited (JP) 2012-03-07 EP disclosed
US-20110281040-A1 LIQUID CRYSTAL DISPLAY ELEMENT, POSITIVE TYPE RADIATION SENSITIVE COMPOSITION, INTERLAYER INSULATING FILM FOR LIQUID CRYSTAL DISPLAY ELEMENT, AND FORMATION METHOD THEREOF JSR CORPORATION (JP) 2011-11-17 US disclosed
US-20100261705-A1 CARBOSTYRIL COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. 2010-10-14 US disclosed
US-7777038-B2 Carbostyril compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-08-17 US disclosed
US-7749678-B2 contains sulfonium compound; improved line edge roughness and pattern profile, and contrast of sensitivity and dissolution in extreme ultraviolet exposure FUJIFILM CORPORATION (JP) 2010-07-06 US disclosed
EP-0201033-A2 A method for processing silver halide color photographic materials KONICA CORPORATION (JP) 1986-11-12 EP disclosed
EP-0200206-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-11-05 EP disclosed
EP-0199351-A2 Silver halide photographic material KONICA CORPORATION (JP) 1986-10-29 EP disclosed
EP-0199604-A2 Processing method for light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-10-29 EP disclosed
EP-0187521-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1986-07-16 EP disclosed
EP-0185506-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1986-06-25 EP disclosed
EP-0182486-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-05-28 EP disclosed
EP-0178794-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-04-23 EP disclosed
EP-0178165-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261705-A1 CARBOSTYRIL COMPOUND GTF2F1, F3, GTF2F2 CA1 2592/4885CA2 254/4885CA9 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.