Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 3/20 | 0.58 |
| ▸ | SELL | P14151 | 1/20 | 0.57 |
| ▸ | SELP | P16109 | 1/20 | 0.57 |
| ▸ | ACMSD | Q8TDX5 | 5/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152464 | 0.86 | ACMSD (0.55) | HNF4ASELLSELPACMSDDHFR | |
| SCHEMBL481375 | 0.85 | MAPT (0.44) | HNF4ASELLSELPACMSDDHFR | |
| SCHEMBL7026199 | 0.84 | SELL (0.57) | HNF4ASELLSELPACMSDDHFR | |
| SCHEMBL31509453 | 0.84 | SELL (0.57) | HNF4ASELLSELPACMSDDHFR | |
| SCHEMBL10823677 | 0.84 | HNF4A (0.50) | HNF4ASELLSELPACMSDDHFR | |
| SCHEMBL28492569 | 0.83 | MEN1 (0.51) | ALDH1A1KDM4EHPGDSMN1; SMN2AKR1C3 | |
| SCHEMBL29945054 | 0.82 | ACMSD (0.52) | HNF4ASELLSELPACMSDDHFR | |
| SCHEMBL8001214 | 0.82 | HNF4A (0.67) | HNF4ASELLSELPACMSDDHFR | |
| SCHEMBL14689993 | 0.81 | HNF4A (0.55) | HNF4ASELLSELPACMSDDHFR | |
| SCHEMBL10823673 | 0.81 | FTO (0.61) | HNF4ASELLSELPACMSDDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057503-B1 | PRODUCTION OF HYDROXY ARYLOPHENONES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-20 | — | — | EP | disclosed |
| US-4453010-A | Production of hydroxy arylophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-05 | — | — | US | disclosed |
| EP-0057503-A1 | Production of hydroxy arylophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-08-11 | — | — | EP | disclosed |