Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4446557 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL8276606 | 0.87 | TSHR (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22878514 | 0.87 | LMNA (0.40) | SLC6A2SLC6A4SLC6A3TDP1MAPT | |
| SCHEMBL8322058 | 0.87 | TSHR (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14208437 | 0.85 | SLC6A2 (0.34) | SLC6A2SLC6A4 | |
| SCHEMBL13900574 | 0.83 | — | — | |
| SCHEMBL13312874 | 0.83 | — | — | |
| SCHEMBL3656270 | 0.83 | — | — | |
| SCHEMBL8780334 | 0.83 | LMNA (0.41) | LMNA | |
| SCHEMBL8492819 | 0.83 | MAPT (0.35) | HTR2AHRH1TDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431751-B1 | Polymeric quaternary ammonium compounds with vicinal hydroxy groups | ALCON RESEARCH, LTD. (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431751-B1 | Polymeric quaternary ammonium compounds with vicinal hydroxy groups | ALCON RESEARCH, LTD. (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431751-B1 | Polymeric quaternary ammonium compounds with vicinal hydroxy groups | ALCON RESEARCH, LTD. (US) | 2013-04-30 | — | — | US | disclosed |
| EP-0069424-B1 | PROCESS FOR THE SELECTIVE REDUCTION OF A 14, 17-DIOXO-8,4-SECO-STEROID | AKZO N.V. (NL) | 1985-05-29 | — | — | EP | disclosed |
| EP-0069424-A1 | Process for the selective reduction of a 14, 17-dioxo-8,4-seco-steroid | AKZO N.V. (NL) | 1983-01-12 | — | — | EP | disclosed |