SCHEMBL8780334

SCHEMBL8780334

CCCC(O)C(O)CN(C)C

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8780312 0.85 SPHK1 (0.40) LMNA
SCHEMBL8780338 0.83 SPHK1 (0.48) LMNA
SCHEMBL4446557 0.83 SLC6A2 (0.34) LMNA
SCHEMBL11026909 0.83 SLC6A2 (0.34) LMNA
SCHEMBL13476921 0.80 LMNA (0.55) LMNATSHR
SCHEMBL104878 0.80 LMNA (0.55) LMNATSHR
SCHEMBL8780306 0.79 LMNA (0.41) LMNATSHR
SCHEMBL8492819 0.79 MAPT (0.35) TSHR
SCHEMBL21555754 0.78 LMNA (0.32) LMNA
SCHEMBL8322058 0.78 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601668-B1 Epoxy resin composition SHELL INT RESEARCH (NL) 1997-03-19 EP disclosed
EP-0601668-A2 Epoxy resin composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1994-06-15 EP disclosed