SCHEMBL4446557

SCHEMBL4446557

CN(C)CC(O)C(O)CN(C)C

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.32
DNM1 Q05193 2/20 0.31
HIF1A Q16665 1/20 0.31
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11026909 1.00 SLC6A2 (0.34) SLC6A2SLC6A4SLC6A3HTR2AHRH1
SCHEMBL8276606 0.87 TSHR (0.35) SLC6A2SLC6A4SLC6A3
SCHEMBL22878514 0.87 LMNA (0.40) SLC6A2SLC6A4SLC6A3TDP1MAPT
SCHEMBL8322058 0.87 TSHR (0.35) SLC6A2SLC6A4SLC6A3
SCHEMBL14208437 0.85 SLC6A2 (0.34) SLC6A2SLC6A4
SCHEMBL13900574 0.83
SCHEMBL13312874 0.83
SCHEMBL3656270 0.83
SCHEMBL8780334 0.83 LMNA (0.41) LMNA
SCHEMBL8492819 0.83 MAPT (0.35) HTR2AHRH1TDP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115624-A1 BORON COMPOUNDS, RELATED LIPID PARTICLES, LIPOPLEXES, COMPOSITIONS, METHODS OF USE, AND METHODS OF MAKING UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2025-04-10 US disclosed
EP-4514810-A1 BORON COMPOUNDS, RELATED LIPID PARTICLES, LIPOPLEXES, COMPOSITIONS, METHODS OF USE, AND METHODS OF MAKING University Of Louisville Research Foundation, Inc. (US) 2025-03-05 EP disclosed
WO-2023212623-A1 BORON COMPOUNDS, RELATED LIPID PARTICLES, LIPOPLEXES, COMPOSITIONS, METHODS OF USE, AND METHODS OF MAKING UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2023-11-02 WO disclosed
US-8361779-B2 Buffer compounds SACHEM, INC. (US) 2013-01-29 US disclosed
US-20120129240-A1 BUFFER COMPOUNDS SACHEM, INC. 2012-05-24 US disclosed
US-7598421-B2 Materials for the delivery of biologically-active material to cells UCL BIOMEDICA PLC (GB) 2009-10-06 US disclosed
US-7598421-B2 Materials for the delivery of biologically-active material to cells UCL BIOMEDICA PLC (GB) 2009-10-06 US disclosed
US-7598421-B2 Materials for the delivery of biologically-active material to cells UCL BIOMEDICA PLC (GB) 2009-10-06 US disclosed
US-20050245446-A1 Materials for the delivery of biologically-active material to cells NANOGENICS LIMITED (GB) 2005-11-03 US disclosed
EP-1506019-A1 COMPLEXES FOR THE DELIVERY OF BIOLOGICALLY-ACTIVE MATERIAL TO CELLS University College London (GB) 2005-02-16 EP disclosed
WO-2003094974-A1 COMPLEXES FOR THE DELIVERY OF BIOLOGICALLY-ACTIVE MATERIAL TO CELLS UNIVERSITY COLLEGE LONDON (GB) 2003-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245446-A1 Materials for the delivery of biologically-active material to cells ITGB1, ITGA2B, ITGB2 SLC6A2 4020/4885SLC6A4 4198/4885SLC6A3 4327/4885
US-20250115624-A1 BORON COMPOUNDS, RELATED LIPID PARTICLES, LIPOPLEXES, COMPOSITIONS, METHODS OF USE, AND METHODS OF MAKING LIPA, LIPC, ABHD16A SLC6A2 3320/4885SLC6A4 4496/4885SLC6A3 4116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.