Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Altretamine SCHEMBL4206 | 0.56 | LMNA (1.00) | LMNACYP1A2THRBBLMCREBBP | |
| Altretamine SCHEMBL2354769 | 0.56 | LMNA (1.00) | LMNACYP1A2THRBBLMCREBBP | |
| Altretamine SCHEMBL10481678 | 0.54 | LMNA (0.92) | LMNACYP1A2THRBBLMCREBBP | |
| Altretamine SCHEMBL20770606 | 0.52 | LMNA (0.85) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL4956264 | 0.52 | LMNA (0.50) | LMNACYP1A2THRBBLMCREBBP | |
| Altretamine SCHEMBL21612149 | 0.50 | LMNA (0.79) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL7537282 | 0.48 | HSP90AB1 (0.48) | LMNA | |
| SCHEMBL1445049 | 0.47 | — | — | |
| SCHEMBL19275166 | 0.47 | — | — | |
| Hydrochloric Acid SCHEMBL9362771 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078784-B1 | THIO-SUBSTITUTED-1,3,5-TRIAZINE-DIAMINES AND -TRIAMINES USEFUL AS PREVULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4460769-A | Thio-amino-1,3,5-triazines | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0078784-A1 | Thio-substituted-1,3,5-triazine-diamines and -triamines useful as prevulcanization inhibitors | MONSANTO COMPANY (US) | 1983-05-11 | — | — | EP | disclosed |
| US-4380609-A | Prevulcanization inhibitors of thio-triazine-amines for rubber | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | disclosed |