Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | BAX | Q07812 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | ACACA | Q13085 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056670 | 0.88 | ESR1 (0.67) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL15940348 | 0.86 | SRD5A2 (0.58) | LTA4HSRD5A2ACACBACACAGRIN1 | |
| SCHEMBL7039574 | 0.86 | MMP3 (0.68) | LMNAPTGS1ESR1ESR2MEN1 | |
| SCHEMBL14421265 | 0.86 | ESR1 (0.70) | LTA4HNR1H2BAXSRD5A2ESR1 | |
| SCHEMBL12804905 | 0.86 | ESR1 (0.70) | LTA4HNR1H2BAXSRD5A2ESR1 | |
| SCHEMBL5488305 | 0.86 | ESR1 (0.70) | LTA4HNR1H2BAXSRD5A2ESR1 | |
| SCHEMBL10053900 | 0.84 | SRD5A2 (0.61) | LTA4HNR1H2BAXSRD5A2ACACB | |
| SCHEMBL7938048 | 0.84 | MMP3 (0.71) | LMNAPTGS1ESR1ESR2MEN1 | |
| SCHEMBL5374943 | 0.84 | LTA4H (0.86) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL25960632 | 0.84 | LTA4H (0.77) | LTA4HNR1H2BAXLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120187392-A1 | IMIDAZOPYRIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS CONTAINING SAME | IDEMITSU KOSAN CO., LTD (JP) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120187392-A1 | IMIDAZOPYRIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS CONTAINING SAME | TPMT, SLC30A5, IDH2 | LTA4H 4469/4885NR1H2 4020/4885BAX 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.